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Select item 95281621.

Parental genomes segregate into distinct blastomeres during multipolar zygotic divisions leading to mixoploid and chimeric blastocysts

Tine De Coster, Heleen Masset, Olga Tšuiko, Maaike Catteeuw, Yan Zhao, Nicolas Dierckxsens, Ainhoa Larreategui Aparicio, Eftychia Dimitriadou, Sophie Debrock, Karen Peeraer, Marta de Ruijter-Villani, Katrien Smits, Ann Van Soom, Joris Robert Vermeesch

Genome Biol. 2022; 23: 201. Published online 2022 Oct 3. doi: 10.1186/s13059-022-02763-2

PMCID:: PMC9528162

Article PDF–3.9M

Select item 53763192.

Mouse blastomeres acquire ability to divide asymmetrically before compaction

Monika Humięcka, Marcin Szpila, Piotr Kłoś, Marek Maleszewski, Katarzyna Szczepańska

PLoS One. 2017; 12(3): e0175032. Published online 2017 Mar 31. doi: 10.1371/journal.pone.0175032

PMCID:: PMC5376319

Article PDF–1.5M

Select item 81601713.

Totipotency of mouse zygotes extends to single blastomeres of embryos at the four-cell stage

Marino Maemura, Hiroaki Taketsuru, Yuki Nakajima, Ruiqi Shao, Ayaka Kakihara, Jumpei Nogami, Yasuyuki Ohkawa, Yu-ichi Tsukada

Sci Rep. 2021; 11: 11167. Published online 2021 May 27. doi: 10.1038/s41598-021-90653-1

PMCID:: PMC8160171

Article PDF–13M

Select item 85637124.

Developmental capacity is unevenly distributed among single blastomeres of 2-cell and 4-cell stage mouse embryos

Katarzyna Krawczyk, Ewa Kosyl, Karolina Częścik-Łysyszyn, Tomasz Wyszomirski, Marek Maleszewski

Sci Rep. 2021; 11: 21422. Published online 2021 Nov 2. doi: 10.1038/s41598-021-00834-1

PMCID:: PMC8563712

Article PDF–6.8M

Select item 55578985.

Totipotency segregates between the sister blastomeres of two-cell stage mouse embryos

E. Casser, S. Israel, A. Witten, K. Schulte, S. Schlatt, V. Nordhoff, M. Boiani

Sci Rep. 2017; 7: 8299. Published online 2017 Aug 15. doi: 10.1038/s41598-017-08266-6

PMCID:: PMC5557898

Article PDF–5.0M

Select item 63386096.

Single blastomeres as a source of mouse embryonic stem cells: effect of genetic background, medium supplements, and signaling modulators on derivation efficiency

Marta Vila-Cejudo, Ot Massafret, Josep Santaló, Elena Ibáñez

J Assist Reprod Genet. 2019 Jan; 36(1): 99–111. Published online 2018 Nov 14. doi: 10.1007/s10815-018-1360-9

PMCID:: PMC6338609

Article PDF–13M

Select item 104254847.

The aryl hydrocarbon receptor directs the differentiation of murine progenitor blastomeres

Chia-I. Ko, Jacek Biesiada, Hesbon A. Zablon, Xiang Zhang, Mario Medvedovic, Alvaro Puga

Cell Biol Toxicol. 2023; 39(4): 1657–1676. Published online 2022 Aug 27. doi: 10.1007/s10565-022-09755-9

PMCID:: PMC10425484

Article PDF–7.5M

Select item 105911818.

Blastomeres of 8-cell mouse embryos differ in their ability to generate embryonic stem cells and produce lines with different transcriptional signatures

Sandra Alonso-Alonso, Anna Esteve-Codina, Beatriz Martin-Mur, Lucia Álvarez-González, Aurora Ruiz-Herrera, Josep Santaló, Elena Ibáñez

Front Cell Dev Biol. 2023; 11: 1274660. Published online 2023 Oct 9. doi: 10.3389/fcell.2023.1274660

PMCID:: PMC10591181

Article PDF–3.7M

Select item 96049489.

Association between the morphokinetics of in-vitro-derived bovine embryos and the transcriptomic profile of the derived blastocysts

Shira Yaacobi-Artzi, Dorit Kalo, Zvi Roth

PLoS One. 2022; 17(10): e0276642. Published online 2022 Oct 26. doi: 10.1371/journal.pone.0276642

PMCID:: PMC9604948

Article PDF–3.0M

Select item 756147210.

Establishment of a relationship between blastomere geometry and YAP localisation during compaction

Christophe Royer, Karolis Leonavicius, Annemarie Kip, Deborah Fortin, Kirtirupa Nandi, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Shankar Srinivas

Development. 2020 Oct 1; 147(19): dev189449. Published online 2020 Oct 9. doi: 10.1242/dev.189449

PMCID:: PMC7561472

Article

Select item 639996811.

Systems based analysis of human embryos and gene networks involved in cell lineage allocation

H. L. Smith, A. Stevens, B. Minogue, S. Sneddon, L. Shaw, L. Wood, T. Adeniyi, H. Xiao, P. Lio, S. J. Kimber, D. R. Brison

BMC Genomics. 2019; 20: 171. Published online 2019 Mar 5. doi: 10.1186/s12864-019-5558-8

PMCID:: PMC6399968

Article PDF–2.6M

Select item 542836112.

Medaka insulin-like growth factor-2 supports self-renewal of the embryonic stem cell line and blastomeres in vitro

Yongming Yuan, Yunhan Hong

Sci Rep. 2017; 7: 78. Published online 2017 Mar 6. doi: 10.1038/s41598-017-00094-y

PMCID:: PMC5428361

Article PDF–9.1M

Select item 639641913.

Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion

Brittany L. Daughtry, Jimi L. Rosenkrantz, Nathan H. Lazar, Suzanne S. Fei, Nash Redmayne, Kristof A. Torkenczy, Andrew Adey, Melissa Yan, Lina Gao, Byung Park, Kimberly A. Nevonen, Lucia Carbone, Shawn L. Chavez

Genome Res. 2019 Mar; 29(3): 367–382. doi: 10.1101/gr.239830.118

PMCID:: PMC6396419

Article PDF–15M

Select item 722046414.

The impacts of the number of prefreeze and postthaw blastomeres on embryo implantation potential: A systematic analysis

Yu-jiang Wang, Wen-juan Liu, Lin Fan, Zi-tao Li, Yu-qiang Huang, Chuang-qi Chen, Dun Liu, Xi-qian Zhang, Feng-hua Liu

Medicine (Baltimore) 2020 Mar; 99(13): e19591. Published online 2020 Mar 27. doi: 10.1097/MD.0000000000019591

PMCID:: PMC7220464

Article PDF–403K

Select item 898289415.

Cortical softening elicits zygotic contractility during mouse preimplantation development

Özge Özgüç, Ludmilla de Plater, Varun Kapoor, Anna Francesca Tortorelli, Andrew G. Clark, Jean-Léon Maître

PLoS Biol. 2022 Mar; 20(3): e3001593. Published online 2022 Mar 24. doi: 10.1371/journal.pbio.3001593

PMCID:: PMC8982894

Article PDF–2.7M

Select item 736097216.

Trophoblast lineage specification in the mammalian preimplantation embryo

Yayoi Toyooka

Reprod Med Biol. 2020 Jul; 19(3): 209–221. Published online 2020 Jul 2. doi: 10.1002/rmb2.12333

PMCID:: PMC7360972

Article PDF–908K

Select item 688441717.

Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution

E Casser, S Wdowik, S Israel, A Witten, S Schlatt, V Nordhoff, M Boiani

Mol Hum Reprod. 2019 Nov; 25(11): 729–744. Published online 2019 Sep 4. doi: 10.1093/molehr/gaz051

PMCID:: PMC6884417

Article PDF–277M

Select item 265246218.

Vitrification of isolated mice blastomeres using a closed loading device

Amr Kader, Ashok Agarwal, Rakesh Sharma, Tommaso Falcone

Reprod Biol Endocrinol. 2009; 7: 17. Published online 2009 Feb 19. doi: 10.1186/1477-7827-7-17

PMCID:: PMC2652462

Article PDF–287K

Select item 901313019.

A decade of molecular preimplantation genetic diagnosis of 350 blastomeres for beta-thalassemia combined with HLA typing, aneuploidy screening and sex selection in Iran

Yeganeh Keshvar, Solmaz Sabeghi, Zohreh Sharifi, Kiyana Sadat Fatemi, Panti Fouladi, Shahrzad Younesi Khah, Faezeh Rahiminejad, Atefeh Joudaki, Masoume Amini, Hamideh Bagherian, Marefat Ghaffari Novin, Mansoureh Movahedin, Marzieh Mojbafan, Sirous Zeinali

BMC Pregnancy Childbirth. 2022; 22: 330. Published online 2022 Apr 15. doi: 10.1186/s12884-022-04660-9